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| Williams,Carey A.. |
| Evidence of oxidative stress in horses has been described in reports dealing with intense and endurance exercise. Oxidative stress occurs when antioxidant systems are insufficient causing oxidation to potentially damage DNA, proteins, and lipids, and contribute to degenerative changes. Vitamin E is the most commonly supplemented antioxidant in horses and has been shown that horses in exercise conditioning may require higher intakes of vitamin E than recommended. Also in various species vitamin C potentiates the effects of vitamin E; however, under maintenance conditions horses have the ability to synthesize sufficient ascorbate, the demand increases as stress on the body is increased. Competitive endurance horses were estimated to consume 1.2 to 5-times... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Equine; Lipoic acid; Oxidative stress; Vitamin E. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982010001300017 |
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| Bassi,E.; Liberman,M.; Martinatti,M.K.; Bortolotto,L.A.; Laurindo,F.R.M.. |
| Vascular calcification decreases compliance and increases morbidity. Mechanisms of this process are unclear. The role of oxidative stress and effects of antioxidants have been poorly explored. We investigated effects of the antioxidants lipoic acid (LA) and tempol in a model of atherosclerosis associated with elastocalcinosis. Male New Zealand white rabbits (2.5-3.0 kg) were fed regular chow (controls) or a 0.5% cholesterol (chol) diet+104 IU/day vitamin D2 (vitD) for 12 weeks, and assigned to treatment with water (vehicle, n=20), 0.12 mmol·kg-1·day-1 LA (n=11) or 0.1 mmol·kg-1·day-1 tempol (n=15). Chol+vitD-fed rabbits developed atherosclerotic plaques associated with expansive remodeling, elastic fiber disruption, medial calcification, and increased... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidants; Vascular calcification; Atherosclerosis; Oxidative stress; Lipoic acid. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000200119 |
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